Therapeutic benefits of Moringa oleifera: A Mini Review

Authors

  • Sunil Kumar Prajapati Professor, Institute of Pharmacy, Bundelkhand University, Jhansi, India
  • Vijay Kumar Tilak Apex Professional University, Pasighat, Arunachal Pradesh-791102, India
  • Ram Chand Dhakar Hospital Pharmacy, SRG Hospital & Medical College Jhalawar, Rajasthan, India-326001 https://orcid.org/0000-0001-8250-8489
  • Rajeshwar Kamal Kant Arya Assistant Professor, Department of Pharma sciences, Kumaun University Nainital, India
  • Jitendra Nagar Associate Professor, Department of ENT, Jhalawar Medical College, Jhalawar, Rajasthan, India
  • Chaman Nagar B. J. Medical College, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.22270/ijmspr.v6i2.80

Keywords:

Oral diseases, anti-diabetic, Moringa oleifera, anti-inflammatory

Abstract

There are about thirteen species of Moringa trees in the family Moringaceae.  Moringa oleifera Lam.  (synonym:  Moringa pterygosperma  Gaertn.)  is the most widely known species and reported many therapeutics uses in previous years. All part of the Moringa tree is useful in some way and people depends on it for their livelihood. The leaves of the Moringa tree are an excellent source of Nutrients like Minerals, Protein and Vitamins (A and C). Moringa tree has approximately 46 antioxidants and it is one of the cheapest sources of natural anti-oxidants. Anti-oxidants supply the free atoms needed by the human body and mitigate the effect of free radicals. M. oleifera contains active compounds such as flavonoids, tannins, saponins, alkaloids, phenolics, and triterpenoids which possess antibacterial effects. Moringa oleifera has high mineral and protein content and has been previously investigated for its potential in treating different oral soft tissue diseases.  Present review summarises the various medicinal uses of Moringa oleifera.

Keywords: Moringa oleifera, anti-inflammatory, Oral diseases, anti-diabetic

Author Biographies

Sunil Kumar Prajapati, Professor, Institute of Pharmacy, Bundelkhand University, Jhansi, India

Professor, Institute of Pharmacy, Bundelkhand University, Jhansi, India

Vijay Kumar Tilak, Apex Professional University, Pasighat, Arunachal Pradesh-791102, India

Apex Professional University, Pasighat, Arunachal Pradesh-791102, India

Ram Chand Dhakar, Hospital Pharmacy, SRG Hospital & Medical College Jhalawar, Rajasthan, India-326001

Hospital Pharmacy, SRG Hospital & Medical College Jhalawar, Rajasthan, India-326001

Rajeshwar Kamal Kant Arya, Assistant Professor, Department of Pharma sciences, Kumaun University Nainital, India

Assistant Professor, Department of Pharma sciences, Kumaun University Nainital, India

Jitendra Nagar, Associate Professor, Department of ENT, Jhalawar Medical College, Jhalawar, Rajasthan, India

Associate Professor, Department of ENT, Jhalawar Medical College, Jhalawar, Rajasthan, India

Chaman Nagar, B. J. Medical College, Ahmedabad, Gujarat, India

B.J. Medical College, Ahmedabad, Gujarat, India

References

Dhakar RC, Maurya SD, Pooniya BK, Bairwa N, Gupta M, S. Moringa: The herbal gold to combat malnutrition. Chron Young Sci 2011; 2:119-25. https://doi.org/10.4103/2229-5186.90887

Dahot MU, Memon AR, Nutritive significance of oil extracted from Moringa oleifera seeds. J Pharm Univ Kar 1985; 3:75-80

Ram J. Moringa a highly nutritious vegetable tree, Tropical Rural and Island/ Atoll Development Experimental Station (TRIADES), Technical Bulletin. 1994; 2.

Abrams B, Duncan D, Hertz Piccioto I. A prospective study of dietary intake and acquired immune deficiency syndrome in HIV sero-positive homosexsual men. J Acquir Immune Defic Syndr 1993; 8:949-58.

Anwar F, Bhanger MI. Analytical characterization of Moriga oleifera seed oil growth in temperate region of Pakistan. J Agric Food Chem 2003; 51:6558- 63. https://doi.org/10.1021/jf0209894 PMid:14558778

Prakash AO. Ovarian response to aqueous extract of Moringa oleifera during early pregnancy in rats. Fitoterapia 1988; 59:89-96

Singh U, Dwivedi C, Kulsum U, Verma N, Saraf S, Pradhan D. Phytochemistry and Medicinal Uses of Moringa Oleifera: An Overview. Journal of Drug Delivery and Therapeutics, 2017;7(6):104-16 https://doi.org/10.22270/jddt.v7i6.1522

El-sharkawy R.T., El-kammar H.A., Obeid R.F., Bdelkhalek A.A. Effects of moringa oleifera aqueous leaf extract on submandibular salivary glands of diabetic albino rats. Egypt. Dent. J. 2018; 64(Issue 2-April):1293-1303. https://doi.org/10.21608/edj.2018.77385

Elkammar Hala, Obeid Raneem F., Radwa T.E. 2019. Potential Therapeitic Effect of Moringa Oleifera on Tongue; pp. 2-8. (June) [Google Scholar]

Ajit K, Choudhary BK, Bandyopadhyay NG (2002). Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol, 84, 105-108. https://doi.org/10.1016/S0378-8741(02)00144-7 PMid:12499084

Francis JA, Jayaprakasam B, Olson LK, et al (2004). Insulin secretagogues from Moringa oleifera with cyclooxygenase enzyme and lipid peroxidation inhibiting activities. Helvitica Chimica Acta, 87, 317-26; https://doi.org/10.1002/hlca.200490029

Ulvian F and Yusriadi KK. Pengaruh Gel Ekstrak Daun Sirih Merah (Piper crocatum Ruiz &Pav) Terhadap Penyembuhan Luka Bakar Pada Kelinci. Galenika Journal of Pharmacy; 2016;2(2): 103-110. https://doi.org/10.22487/j24428744.2016.v2.i2.5977

Lee S, Lee I, Mar W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Arch. Pharm. Res. 2003;26:832-839. https://doi.org/10.1007/BF02980029 PMid:14609132

Ulfa M, Hendrarti W, Muhram PN. Formulasi Gel Ekstrak Daun Kelor (Moringa oleifera Lam.) Sebagai Anti Inflamasi Topikal Pada Tikus (Rattus novergicus). J. Pharm. Med. Sci. 2016;1: 30-35.

Nanaryain MF. Efek antiinflamasi sediaan krim ekstrak etanol daun kelor (moringa oleifera lam.) Pada tikus putih jantan yang diinduksi karagenin. Surakarta: Universitas Setiabudi. 2016.

Singh U, Dwivedi C, Kulsum U, Verma N, Saraf S, Pradhan DK , Phytochemistry and medicinal uses of moringa oleifera: an overview,Journal of Drug Delivery and Therapeutics. 2017; 7(6):104-116 https://doi.org/10.22270/jddt.v7i6.1522

Gilani AH, Aftab K, Suria A et al.. Pharmacological studies on hypotensive and spasmodic activities of pure compounds from Moringa oleifera. Phytother Res 1994a; 8:87-91. https://doi.org/10.1002/ptr.2650080207

Pal SK, Mukherjee PK, Saha BP. Studies on the antiulcer activity of Moringa oleifera leaf extract on gastric ulcer models in rats. Phytother Res 1995a; 9:463-465. https://doi.org/10.1002/ptr.2650090618

Gilani AH, Janbaz KH, Shah BH. 1997. Quercetin exhibits hepatoprotective activity in rats. Biochem Soc Trans 25: 85. https://doi.org/10.1042/bst025s619 PMid:9450047

Ruckmani K, Kavimani S, Anandan R, Jaykar B.. Effect of Moringa oleifera Lam on paracetamol-induced hepatotoxicity Indian J Pharm Sci1998; 60:33-35

Aboobecker, S., Bajpai, A., Srivastava, R., Tewari, R., & Hooda, M. To Study Analgesic, Hypoglycemic and Hepatoprotective Activity of Moringa olefera Leaf Extract in Albino Wistar Rats. Journal of Drug Delivery and Therapeutics, 2019;9(4-A):730-736.

Singh GP, Sharma SK(2012). Antimicrobial evaluation of leaf extract of Moringa oleifera Lam. Int Res J Pharm, 3, 1-4.

Elgamily H, Moussa A, Elboraey A, EL-Sayed H, Al-Moghazy M, Abdalla A. Microbiological Assessment of Moringa Oleifera Extracts and Its Incorporation in Novel Dental Remedies against Some Oral Pathogens. Open Access Maced J Med Sci. 2016; 4(4):585-90. https://doi.org/10.3889/oamjms.2016.132 PMid:28028395 PMCid:PMC5175503

Maurya, S. and Singh A. (2014). Clinical Efficacy of Moringa oleifera Lam. Stems Bark in Urinary Tract Infections. Hindawi International Scholarly Research Notices. [Online]. Available : https://www.hindawi.com/journals/isrn/2014/906843/ https://doi.org/10.1155/2014/906843 PMid:27437504 PMCid:PMC4897232

Marsh PD. Microbial ecology of dental plaque and its significance in health and disease. Adv Dent Res. 1994; 8:263-271. https://doi.org/10.1177/08959374940080022001 PMid:7865085

Jwa SK. Efficacy of Moringa oleifera Leaf Extracts against Cariogenic Biofilm. Prev Nutr Food Sci. 2019; 24(3):308-312. doi: https://doi.org/10.3746/pnf.2019.24.3.308 PMid:31608256 PMCid:PMC6779079

Rao PK, Rao DB, Kiran C, et al. In vitro antibacterial activity of Moringa oleifera against dental plaque bacteria. Journal of Pharmacy Research 2011; 4(3):695-742

Carranza JB, Molina PG, Ortañez JJR, et al. Flavonoids, alkaloids and tannins of three varieties of horse radish (Moringa oleifera Lam.) extracts: potential components of toothpastes. International Scholars Conference Proceeding 2017; 5(1):30-3.

Published

15-06-2020

How to Cite

Prajapati, S. K., Tilak, V. K. ., Dhakar, R. C. ., Arya, R. K. K. ., Nagar, J. ., & Nagar, C. . (2020). Therapeutic benefits of Moringa oleifera: A Mini Review. International Journal of Medical Sciences and Pharma Research, 6(2), 1–4. https://doi.org/10.22270/ijmspr.v6i2.80