The Effectiveness of Curcumin on Dysmenorrhea

Authors

  • Shubhangi Shrivastav Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207
  • Ravindra Tyagi Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207
  • Meenakshi Singh Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207
  • Sudhanshu Jha Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

DOI:

https://doi.org/10.22270/ijmspr.v8i4.51

Keywords:

Menstrual cycle, Dysmenorrhea, Curcumin, Curcuma longa

Abstract

Menstruation is a cycle of oocyte release and preparing uterus for possible pregnancy if fertilization occurs. It begins at puberty and ends at menopause with an average duration of 28 days. Primary menstrual pain is a problem for women throughout the world that can affect daily life. Painful menstruation, also known as dysmenorrhea, is one of the most common women’s problems. Most women begin having dysmenorrhea during adolescence, usually within four to five years of the first menstrual period. Painful periods become less common as women age. For the treatment of dysmenorrheal much herbal medicine are use. Curcumin is one of the best phytochemical which is isolated from Curcuma longa L., is a fat-soluble natural compound which accumulative evidences have demonstrated that it can use to treat dymenorrhea. The objective of this paper is to analyze through literature regarding primary dysmenorrhea and natural herbal used to relieve the pain. Data from previous research show that curcumin and is the best candidates for relieving primary menstrual pain.

Keywords: Menstrual cycle, Dysmenorrhea, Curcumin, Curcuma longa

Author Biographies

Shubhangi Shrivastav, Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Ravindra Tyagi, Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Meenakshi Singh, Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Sudhanshu Jha, Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

Department of Pharmacy, Vishveshwarya Group of Institutions, G.T. Road Greater Noida Phase II Noida, Uttar Pradesh 203207

References

Thiyagarajan DK, Basit H, Jeanmonod R. Physiology, menstrual cycle. In Stat Pearls 2021. Stat Pearls Publishing.

Bernardi M, Lazzeri L, Perelli F, Reis FM, Petraglia F. Dysmenorrhea and related disorders. F1000Research. 2017; 6. https://doi.org/10.12688/f1000research.11682.1

Osayande AS, Mehulic S. Diagnosis and initial management of dysmenorrhea. American family physician. 2014; 89(5):341-6.

Habibi N, Huang MS, Gan WY, Zulida R, Safavi SM. Prevalence of primary dysmenorrhea and factors associated with its intensity among undergraduate students: a cross-sectional study. Pain Management Nursing. 2015; 16(6):855-61. https://doi.org/10.1016/j.pmn.2015.07.001

Proctor MM, Farquhar CM. Dysmenorrhoea. BMJ clinical evidence. 2007.

Berkley KJ. Primary dysmenorrhea: an urgent mandate. Pain. 2013; 1(1):8.

Larasati TA, Alatas F. Dismenore primer dan faktor risiko Dismenore primer pada Remaja. Jurnal Majority. 2016; 5(3):79-84.

Parker MA, Sneddon AE, Arbon P. The menstrual disorder of teenagers (MDOT) study: determining typical menstrual patterns and menstrual disturbance in a large population‐based study of Australian teenagers. BJOG: An International Journal of Obstetrics & Gynaecology. 2010; 117(2):185-92. https://doi.org/10.1111/j.1471-0528.2009.02407.x

Chaudhuri A, Singh A, Dhaliwal L. A randomised controlled trial of exercise and hot water bottle in the management of dysmenorrhoea in school girls of Chandigarh, India. Indian J Physiol Pharmacol. 2013; 57(2):114-22.

Daley AJ. Exercise and primary dysmenorrhoea. Sports Medicine. 2008; 38(8):659-70. https://doi.org/10.2165/00007256-200838080-00004

Saleh HS, Mowafy HE, El Hameid A. Stretching or core strengthening exercises for managing primary dysmenorrhea. J Women's Health Care. 2016; 5(295):2167-0420. https://doi.org/10.4172/2167-0420.1000295

Azima S, Bakhshayesh HR, Kaviani M, Abbasnia K, Sayadi M. Comparison of the effect of massage therapy and isometric exercises on primary dysmenorrhea: a randomized controlled clinical trial. Journal of pediatric and adolescent gynecology. 2015; 28(6):486-91. https://doi.org/10.1016/j.jpag.2015.02.003

Brown J, Brown S. Exercise for dysmenorrhoea. Cochrane Database of Systematic Reviews. 2010(2). https://doi.org/10.1002/14651858.CD004142.pub2

Zhang F, Sun M, Han S, Shen X, Luo Y, Zhong D, Zhou X, Liang F, Jin R. Acupuncture for primary dysmenorrhea: an overview of systematic reviews. Evidence-Based Complementary and Alternative Medicine. 2018. https://doi.org/10.1155/2018/8791538

Yang NY, Kim SD. Effects of a yoga program on menstrual cramps and menstrual distress in undergraduate students with primary dysmenorrhea: a single-blind, randomized controlled trial. The Journal of Alternative and Complementary Medicine. 2016; 22(9):732-8. https://doi.org/10.1089/acm.2016.0058

Ortiz MI, Cortés-Márquez SK, Romero-Quezada LC, Murguía-Cánovas G, Jaramillo-Díaz AP. Effect of a physiotherapy program in women with primary dysmenorrhea. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2015; 194:24-9. https://doi.org/10.1016/j.ejogrb.2015.08.008

Wrisnijati D, Wiboworini B, Sugiarto S. Effects of Pineapple Juice and Ginger Drink for Relieving Primary Dysmenorrhea Pain among Adolescents. Indonesian Journal of Medicine. 2019; 4(2):96-104. https://doi.org/10.26911/theijmed.2019.04.02.03

Chen CX, Barrett B, Kwekkeboom KL. Efficacy of oral ginger (Zingiber officinale) for dysmenorrhea: a systematic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2016. https://doi.org/10.1155/2016/6295737

Pattanittum P, Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, Seyfoddin V, Marjoribanks J. Dietary supplements for dysmenorrhoea. Cochrane Database of Systematic Reviews. 2016(3). https://doi.org/10.1002/14651858.CD002124.pub2

Bajalan Z, Alimoradi Z, Moafi F. Nutrition as a potential factor of primary dysmenorrhea: a systematic review of observational studies. Gynecologic and obstetric investigation. 2019; 84(3):209-24. https://doi.org/10.1159/000495408

Widiatami T, Widyawati MN, Admini A. Study Literature Tentang Pemberian Minuman Kunyit Asam Terhadap Tingkat Nyeri Menstruasi Pada Remaja Putri. Jurnal Kebidanan. 2018; 8(2):139-45. https://doi.org/10.31983/jkb.v8i2.3743

Wulandari A, Rodiani R, Sari RD. Pengaruh Pemberian Ekstrak Kunyit (Curcuma longa linn) dalam Mengatasi Dismenorea. Jurnal Majority. 2018; 7(2):193-7.

Reed BG, Carr BR. The normal menstrual cycle and the control of ovulation. MDText. com. Inc., South Dartmouth MA. 2000.

Najmabadi S, Schliep KC, Simonsen SE, Porucznik CA, Egger MJ, Stanford JB. Menstrual bleeding, cycle length, and follicular and luteal phase lengths in women without known subfertility: A pooled analysis of three cohorts. Paediatric and perinatal epidemiology. 2020; 34(3):318-27. https://doi.org/10.1111/ppe.12644

Purohit A, Jain S, Nema P, Jain DK, Vishwakarma H, Jain PK. A comprehensive review on tailoring an herbal approach for treatment of poly cystic ovarian syndrome. Asian Journal of Dental and Health Sciences. 2022; 2(1):27-32.

Baird DT, Cameron ST, Critchley HO, Drudy TA, Howe A, Jones RL, Lea RG, Kelly RW. Prostaglandins and menstruation. European Journal of Obstetrics & Gynecology and Reproductive Biology. 1996; 70(1):15-7. https://doi.org/10.1016/S0301-2115(96)02568-7

Ricciotti E, FitzGerald GA. Prostaglandins and inflammation. Arteriosclerosis, thrombosis, and vascular biology. 2011; 31(5):986-1000. https://doi.org/10.1161/ATVBAHA.110.207449

Speroff L, Fritz MA, editors. Clinical gynecologic endocrinology and infertility. lippincott Williams & wilkins; 2005.

Harel Z. Dysmenorrhea in adolescents and young adults: an update on pharmacological treatments and management strategies. Expert opinion on pharmacotherapy. 2012; 13(15):2157-70. https://doi.org/10.1517/14656566.2012.725045

Zielińska A, Alves H, Marques V, Durazzo A, Lucarini M, Alves TF, Morsink M, Willemen N, Eder P, Chaud MV, Severino P. Properties, extraction methods, and delivery systems for curcumin as a natural source of beneficial health effects. Medicina. 2020; 56(7):336. https://doi.org/10.3390/medicina56070336

Arihta BR Sembiring, Suryani, Suswati. Effectiveness of turmeric tamarind and warm compression in the dysmenorrhea degression: Non pharmacologic therapy. International Journal of Multidisciplinary Research and Development, 2018; 5(2): 18-23.

Jamila SQ, Pengaruh pemberian minuman kunyit asam terhadap penurunan tingkat nyeri menstruasi (dysmenorrhea) primer pada remaja putri di MTs Nurul Hikmah Kota Surabaya. Infokes, 2018; 8(2):1-7. https://doi.org/10.31983/jkb.v8i2.3743

Sugiharti RK, Sundari RI. Efektivitas minuman kunyit asam dan rempah jahe asam terhadap penurunan skala nyeri haid primer. Medisains. 2018; 16(2):55-9. https://doi.org/10.30595/medisains.v16i2.2714

Asroyo T, Nugraheni TP, Masfiroh MA. Pengaruh Pemberian Minuman Kunyit Asam sebagai Terapi Dismenore terhadap Penurunan Skala Nyeri. Indonesia Jurnal Farmasi. 2020; 4(1):24-8.

Winarso A. Pengaruh minum kunyit asam terhadap penurunan tingkat nyeri dismenorea pada siswi di Madrasah Tsanawiyah Negeri Jatinom Klaten. Interest: Jurnal Ilmu Kesehatan. 2014;3(2).

Anugrahhayyu CA, Darsini N, Sa'adi A. Minuman Kedelai (Glycine max) dan Kombinasi Asam Jawa (Tamarindus indica) dengan Kunyit (Curcuma domestica) dalam Mengurangi Nyeri Haid. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia. 2018; 5(1):1-5. https://doi.org/10.20473/jfiki.v5i12018.1-5

Marsaid M, Nurjayanti D, Rimbaga YA. Efektifitas pemberian ekstrak kunyit asam terhadap penurunan dismenore pada remaja putri. Global Health Science. 2017; 2(2).

Hewlings SJ, Kalman DS. Curcumin: A review of its effects on human health. Foods. 2017; 6(10):92. https://doi.org/10.3390/foods6100092

Hatcher H, Planalp R, Cho J, Torti FM, Torti SV. Curcumin: from ancient medicine to current clinical trials. Cellular and molecular life sciences. 2008; 65(11):1631-52. https://doi.org/10.1007/s00018-008-7452-4

Khayat S, Fanaei H, Kheirkhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial. Complementary therapies in medicine. 2015; 23(3):318-24. https://doi.org/10.1016/j.ctim.2015.04.001

Dyawapur A, Patil NG, Metri L. Effectiveness of cinnamon tea and turmeric water for reducing dysmenorrhoea among degree girls. International Journal of Science and Healthcare Research (www. ijshr. com). 2018; 3(1):88.

Rogers PA, D'Hooghe TM, Fazleabas A, Gargett CE, Giudice LC, Montgomery GW, Rombauts L, Salamonsen LA, Zondervan KT. Priorities for endometriosis research: recommendations from an international consensus workshop. Reproductive sciences. 2009; 16(4):335-46. https://doi.org/10.1177/1933719108330568

Published

15-12-2022

How to Cite

Shrivastav, S. ., Tyagi, R. ., Singh, M. ., & Jha, S. . (2022). The Effectiveness of Curcumin on Dysmenorrhea. International Journal of Medical Sciences and Pharma Research, 8(4), 8–12. https://doi.org/10.22270/ijmspr.v8i4.51