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International Journal of Medical Sciences and Pharma Research
Open Access to Medical Science and Pharma Research
Copyright © 2024 The Author(s): This is an open-access article distributed under the terms of the CC BY-NC 4.0 which permits unrestricted use, distribution, and reproduction in any medium for non-commercial use provided the original author and source are credited
A Review on Widely Used Diagnostic Technique to Rule Out Malnutrition in Children (Under 5 Years)
Shaik Abdul Rasheed *1, Modepalli Poojitha 1, Uppalapati Anusha 1, Maddala Santhi 1, Yerikala Ramesh 2, Yadala Prapurna Chandra 3
|
Article Info: __________________________________________ Article History: Received 08 December 2023 Reviewed 23 January 2024 Accepted 19 February 2024 Published 15 March 2024 __________________________________________ Cite this article as: Rasheed SA, Poojitha M, Anusha U, Santhi M, Ramesh Y, Chandra YP, A Review on Widely Used Diagnostic Technique to Rule Out Malnutrition in Chiildren (Under 5 Years), International Journal of Medical Sciences & Pharma Research, 2024; 10(1):1-6 DOI: http://dx.doi.org/10.22270/ijmspr.v10i1.81 __________________________________________ *Address for Correspondence: Shaik Abdul Rasheed, Vth year Pharm D student, Ratnam Institute of Pharmacy, Pidathapolur (V), Muthukur (M), SPSR Nellore - 524346, Andhra Pradesh, India |
Abstract ____________________________________________________________________________________________________________________ Anthropometric pointers are most effectively used to describe the nutritive status of populations as an expression of the magnitude and distribution of under nutrition. They're less accurate than other styles, still, when it comes to assessing individual nutritive status. In numerous field situations where coffers are oppressively limited, it's possible to use anthropometry as a webbing device to identify individualities at threat of under nutrition. This primary opinion can be followed up with a more elaborate disquisition using other ways. A stubborn continuity of child severe acute malnutrition and continued gaps in program content have made relating styles for expanding the discovery, opinion, and treatment of SAM a critical public health need. There's a growing agreement that making mid-upper arm circumference use more extensively accessible among caregivers and community health workers is an important coming step in farther decentralizing SAM care and adding program content, including the capability of CHWs to treat uncomplicated SAM in community settings. Keywords: Malnutrition, Nutrition, Moderate acute malnutrition, Anthropometry. |
INTRODUCTION
Malnutrition occurs when there's an imbalance between the nutrients your body receives and the nutrients it needs to operate. Malnutrition refers to two general orders of conditions.Undernutrition, characterised by low weight for height, light(low weight for age), and suppressing (low height for age); malnutrition related to micronutrients, characterised by micronutrient scarcities(a lack of essential vitamins and minerals). Overnutrition encompasses rotundity, being fat, andnon-communicable ails linked to food(including diabetes, heart complaint, stroke, and some types of cancer) 1.
Symptoms of malnutrition include 2:
Pale, thick and dry skin, Bruising fluently, Rashes, common pains, Bleeding epoxie, Night blindness, Tenderheartedness in bones.
Over nutrition:
Over nutrition, also known as unbalanced nutrition, is a kind of malnutrition that results from consuming too many nutrients, which can accumulate body fat and negatively impact health (i.e., overweight/obesity).
For kids younger than five:
Weight-for-height more than two standard deviations over the WHO Child Growth Standards median is considered overweight, while weight-for-height larger than three standard deviations above the WHO Child Growth Standards median is considered obesity 3.
Under nutrition:
It is the state in which a person consumes less energy and nutrients than what their body requires to stay healthy.
It is subdivided into four types:
Stunting:
A low height relative to age is called stunting. It is the outcome of persistent or recurring undernutrition, which is typically linked to low socioeconomic status, inadequate mother health and nutrition, recurrent illnesses, and/or improper early feeding and care of infants and young children. Children that are stunted are unable to develop to their full physical and intellectual potential.
Figure 1: Classification of Malnutrition
Wasting:
It is the term for low weight-for-height. Typically, it denotes abrupt and significant weight loss because the person may have had malnutrition or an infectious illness like diarrhoea that contributed to their weight loss. A young kid who is severely or moderately wasted faces a higher chance of not making it, although there is hope for recovery 4.
It is broadly classified into two types:
Severe acute malnutrition (SAM):
It is characterised by an extremely low mid-upper arm circumference, a very low weight-for-height/weight-for-length ratio, or clinical evidence of bilateral pitting oedema.
Diseases associated with SAM:
Marasmus:
Severe undernutrition, or a lack of any of the macronutrients the body needs to operate, such as lipids, proteins, and carbs, is known as marasmus. Marasmus causes the subcutaneous fat and muscle to visibly deteriorate, creating the impression of gaunt people. It results in children's development being stunted.
Kwashiorkor:
Kwashiorkor is a disorder characterised by bilateral extremities oedema and acute protein deficiency. It often affects babies and kids, usually from the time they start weaning until they are five years old. Globally, the sickness affects places of great poverty and extremely severe instances of malnutrition 5.
Marasmic Kwashiorkor:
The third kind of protein-energy malnutrition, known as marasmic kwashiorkor, is a combination of the signs and symptoms of kwashiorkor and marasmus. A person who has marasmic kwashiorkor may: -have abnormally low body mass. - exhibit wasting in certain body parts; - have an abnormal accumulation of fluid in other body sections.
Moderate acute malnutrition (MAM) 6:
Since MAM is less severe, it may be managed with supplemental feedings of an energy-dense food or by increasing the sufficiency of the home diet through nutrition education and counselling.
Under weight:
It refers to children who are underweight for their age. Underweight children might be wasted, stunted, or both.
Micronutrient deficiency 7:
Inadequate consumption of vitamins and minerals, often known as micronutrients, can also be categorised as such. The body needs micronutrients in order to manufacture hormones, enzymes, and other chemicals needed for healthy growth and development. In terms of global public health, iodine, vitamin A, and iron are the most crucial; deficiencies in these nutrients pose a serious risk to the growth and well-being of people everywhere, especially children and expectant mothers in low-income nations.
Diagnostic ways for malnutrition in children 8:
The length of the condition and any pouring reasons, if any, are taken into consideration when diagnosing malnutrition. The main pointers of malnutrition are constantly the clinical history and symptoms, and individual and imaging tests have a little part in the assessment of malnutrition.
To rule out underpinning reasons or conditions that may have contributed to the glutted state, individual testing and imaging examinations could be needed.
Children's height and weight are measured, and the results are compared to maps that indicate the typical height and weight for children in that age group. Some children constantly feellower than their factual age, which might be inherited.
A rapid-fire or substantial dip below a child's prognosticated position may raise enterprises for parents and caregivers since it may be a suggestion of malnutrition. Children that develop more sluggishly might conceivably be undernourished.
Blood tests:
Blood tests similar as those for blood glucose, blood counts, routine urine examinations, coprolite examinations for sponger and worm infestations(which can beget starvation in children), blood protein or albumin situations, testing for HIV, and tests for colorful ails are each considered standard blood tests for children.
It's also advised to check blood iron, folic acid, and vitamin B12 situations. fresh assays for protein estimate include transferrin, retinol- binding protein, andpre-albumin.
Anthropometric pointers of Malnutrition 9-10:
Most anthropometric checks are conducted on preschool children because they grow presto and therefore demonstrate changes in nutritive status more fleetly than any other age group. In addition, this group reflects the immediate social and profitable terrain which affects the health and nutritive situation of an entire population.
Anthropometry has also been used to assess the nutritive status of grown-ups, in particular to estimate rotundity and affiliated problems of overnutrition. For this purpose, a" body- massindicator" is used together with other measures in order to describe overall body composition and fat distribution.
While the growth of community- grounded operation of acute malnutrition(CMAM) programs has vastly increased content of treatment for SAM over the once decade, continued gaps in content and a continuity of SAM have made relating strategic styles for expanding access to care, and chancing the means to work these styles at scale, a critical public health need.
Anthropometry is the determination of nutritive status by physical measures and comparing them to applicable reference maps similar as the WHO weight- for- height reference map.(table 1)
Table 1: Weight-for-length reference chart (below 87 cm)
|
Boys` weight (kg) |
Length |
|
Girls` weight (kg) |
|
||||||
|
-4 SD |
-3 SD |
-2 SD |
-1 SD |
Médian |
(cm) |
Médian |
-1 SD |
-2 SD |
-3 SD |
-4 SD |
|
1.7 |
1.9 |
2.0 |
2.2 |
2.4 |
45 |
2.5 |
2.3 |
2.1 |
1.9 |
1.7 |
|
1.8 |
2.0 |
2.2 |
2.4 |
2.6 |
46 |
2.6 |
2.4 |
2.2 |
2.0 |
1.9 |
|
2.0 |
2.1 |
2.3 |
2.5 |
2.8 |
47 |
2.8 |
2.6 |
2.4 |
2.2 |
2.0 |
|
2.1 |
2.3 |
2.5 |
2.7 |
2.9 |
48 |
3.0 |
2.7 |
2.5 |
2.3 |
2.1 |
|
2.2 |
2.4 |
2.6 |
2.9 |
3.1 |
49 |
3.2 |
2.9 |
2.6 |
2.4 |
2.2 |
|
2.4 |
2.6 |
2.8 |
3.0 |
3.3 |
50 |
3.4 |
3.1 |
2.8 |
2.6 |
2.4 |
|
2.5 |
2.7 |
3.0 |
3.2 |
3.5 |
51 |
3.6 |
3.3 |
3.0 |
2.8 |
2.5 |
|
2.7 |
2.9 |
3.2 |
3.5 |
3.8 |
52 |
3.8 |
3.5 |
3.2 |
2.9 |
2.7 |
|
2.9 |
3.1 |
3.4 |
3.7 |
4.0 |
53 |
4.0 |
3.7 |
3.4 |
3.1 |
2.8 |
|
3.1 |
3.3 |
3.6 |
3.9 |
4.3 |
54 |
4.3 |
3.9 |
3.6 |
3.3 |
3.0 |
|
3.3 |
3.6 |
3.8 |
4.2 |
4.5 |
55 |
4.5 |
4.2 |
3.8 |
3.5 |
3.2 |
|
3.5 |
3.8 |
4.1 |
4.4 |
4.8 |
56 |
4.8 |
4.4 |
4.0 |
3.7 |
3.4 |
|
3.7 |
4.0 |
4.3 |
4.7 |
5.1 |
57 |
5.1 |
4.6 |
4.3 |
3.9 |
3.6 |
|
3.9 |
4.3 |
4.6 |
5.0 |
5.4 |
58 |
5.4 |
4.9 |
4.5 |
4.1 |
3.8 |
|
4.1 |
4.5 |
4.8 |
5.3 |
5.7 |
59 |
5.6 |
5.1 |
4.7 |
4.3 |
3.9 |
|
4.3 |
4.7 |
5.1 |
5.5 |
6.0 |
60 |
5.9 |
5.4 |
4.9 |
4.5 |
4.1 |
|
4.5 |
4.9 |
5.3 |
5.8 |
6.3 |
61 |
6.1 |
5.6 |
5.1 |
4.7 |
4.3 |
|
4.7 |
5.1 |
5.6 |
6.0 |
6.5 |
62 |
6.4 |
5.8 |
5.3 |
4.9 |
4.5 |
|
4.9 |
5.3 |
5.8 |
6.2 |
6.8 |
63 |
6.6 |
6.0 |
5.5 |
5.1 |
4.7 |
|
5.1 |
5.5 |
6.0 |
6.5 |
7.0 |
64 |
6.9 |
6.3 |
5.7 |
5.3 |
4.8 |
|
5.3 |
5.7 |
6.2 |
6.7 |
7.3 |
65 |
7.1 |
6.5 |
5.9 |
5.5 |
5.0 |
|
5.5 |
5.9 |
6.4 |
6.9 |
7.5 |
66 |
7.3 |
6.7 |
6.1 |
5.6 |
5.1 |
|
5.6 |
6.1 |
6.6 |
7.1 |
7.7 |
67 |
7.5 |
6.9 |
6.3 |
5.8 |
5.3 |
|
5.8 |
6.3 |
6.8 |
7.3 |
8.0 |
68 |
7.7 |
7.1 |
6.5 |
6.0 |
5.5 |
|
6.0 |
6.5 |
7.0 |
7.6 |
8.2 |
69 |
8.0 |
7.3 |
6.7 |
6.1 |
5.6 |
|
6.1 |
6.6 |
7.2 |
7.8 |
8.4 |
70 |
8.2 |
7.5 |
6.9 |
6.3 |
5.8 |
|
6.3 |
6.8 |
7.4 |
8.0 |
8.6 |
71 |
8.4 |
7.7 |
7.0 |
6.5 |
5.9 |
|
6.4 |
7.0 |
7.6 |
8.2 |
8.9 |
72 |
8.6 |
7.8 |
7.2 |
6.6 |
6.0 |
|
6.6 |
7.2 |
7.7 |
8.4 |
9.1 |
73 |
8.8 |
8.0 |
7.4 |
6.8 |
6.2 |
|
6.7 |
7.3 |
7.9 |
8.6 |
9.3 |
74 |
9.0 |
8.2 |
7.5 |
6.9 |
6.3 |
|
6.9 |
7.5 |
8.1 |
8.8 |
9.5 |
75 |
9.1 |
8.4 |
7.7 |
7.1 |
6.5 |
|
7.0 |
7.6 |
8.3 |
8.9 |
9.7 |
76 |
9.3 |
8.5 |
7.8 |
7.2 |
6.6 |
|
7.2 |
7.8 |
8.4 |
9.1 |
9.9 |
77 |
9.5 |
8.7 |
8.0 |
7.4 |
6.7 |
|
7.3 |
7.9 |
8.6 |
9.3 |
10.1 |
78 |
9.7 |
8.9 |
8.2 |
7.5 |
6.9 |
|
7.4 |
8.1 |
8.7 |
9.5 |
10.3 |
79 |
9.9 |
9.1 |
8.3 |
7.7 |
7.0 |
|
7.6 |
8.2 |
8.9 |
9.6 |
10.4 |
80 |
10.1 |
9.2 |
8.5 |
7.8 |
7.1 |
|
7.7 |
8.4 |
9.1 |
9.8 |
10.6 |
81 |
10.3 |
9.4 |
8.7 |
8.0 |
7.3 |
|
7.9 |
8.5 |
9.2 |
10.0 |
10.8 |
82 |
10.5 |
9.6 |
8.8 |
8.1 |
7.5 |
|
8.0 |
8.7 |
9.4 |
10.2 |
11.0 |
83 |
10.7 |
9.8 |
9.0 |
8.3 |
7.6 |
|
8.2 |
8.9 |
9.6 |
10.4 |
11.3 |
84 |
11.0 |
10.1 |
9.2 |
8.5 |
7.8 |
|
8.4 |
9.1 |
9.8 |
10.6 |
11.5 |
85 |
11.2 |
10.3 |
9.4 |
8.7 |
8.0 |
|
8.6 |
9.3 |
10.0 |
10.8 |
11.7 |
86 |
11.5 |
10.5 |
9.7 |
8.9 |
8.1 |
|
Boys’ weight (kg) |
Height |
|
Girls’ weight (kg) |
|
||||||
|
-4 SD |
-3 SD |
-2 SD |
-1 SD |
Médian |
(cm) |
Médian |
-1 SD |
-2 SD |
-3 SD |
-4 SD |
|
8.9 |
9.6 |
10.4 |
11.2 |
12.2 |
87 |
11.9 |
10.9 |
10.0 |
9.2 |
8.4 |
|
9.1 |
9.8 |
10.6 |
11.5 |
12.4 |
88 |
12.1 |
11.1 |
10.2 |
9.4 |
8.6 |
|
9.3 |
10.0 |
10.8 |
11.7 |
12.6 |
89 |
12.4 |
11.4 |
10.4 |
9.6 |
8.8 |
|
9.4 |
10.2 |
11.0 |
11.9 |
12.9 |
90 |
12.6 |
11.6 |
10.6 |
9.8 |
9.0 |
|
9.6 |
10.4 |
11.2 |
12.1 |
13.1 |
91 |
12.9 |
11.8 |
10.9 |
10.0 |
9.1 |
|
9.8 |
10.6 |
11.4 |
12.3 |
13.4 |
92 |
13.1 |
12.0 |
11.1 |
10.2 |
9.3 |
|
9.9 |
10.8 |
11.6 |
12.6 |
13.6 |
93 |
13.4 |
12.3 |
11.3 |
10.4 |
9.5 |
|
10.1 |
11.0 |
11.8 |
12.8 |
13.8 |
94 |
13.6 |
12.5 |
11.5 |
10.6 |
9.7 |
|
10.3 |
11.1 |
12.0 |
13.0 |
14.1 |
95 |
13.9 |
12.7 |
11.7 |
10.8 |
9.8 |
|
10.4 |
11.3 |
12.2 |
13.2 |
14.3 |
96 |
14.1 |
12.9 |
11.9 |
10.9 |
10.0 |
|
10.6 |
11.5 |
12.4 |
13.4 |
14.6 |
97 |
14.4 |
13.2 |
12.1 |
11.1 |
10.2 |
|
10.8 |
11.7 |
12.6 |
13.7 |
14.8 |
98 |
14.7 |
13.4 |
12.3 |
11.3 |
10.4 |
|
11.0 |
11.9 |
12.9 |
13.9 |
15.1 |
99 |
14.9 |
13.7 |
12.5 |
11.5 |
10.5 |
|
11.2 |
12.1 |
13.1 |
14.2 |
15.4 |
100 |
15.2 |
13.9 |
12.8 |
11.7 |
10.7 |
|
11.3 |
12.3 |
13.3 |
14.4 |
15.6 |
101 |
15.5 |
14.2 |
13.0 |
12.0 |
10.9 |
|
11.5 |
12.5 |
13.6 |
14.7 |
15.9 |
102 |
15.8 |
14.5 |
13.3 |
12.2 |
11.1 |
|
11.7 |
12.8 |
13.8 |
14.9 |
16.2 |
103 |
16.1 |
14.7 |
13.5 |
12.4 |
11.3 |
|
11.9 |
13.0 |
14.0 |
15.2 |
16.5 |
104 |
16.4 |
15.0 |
13.8 |
12.6 |
11.5 |
|
12.1 |
13.2 |
14.3 |
15.5 |
16.8 |
105 |
16.8 |
15.3 |
14.0 |
12.9 |
11.8 |
|
12.3 |
13.4 |
14.5 |
15.8 |
17.2 |
106 |
17.1 |
15.6 |
14.3 |
13.1 |
12.0 |
|
12.5 |
13.7 |
14.8 |
16.1 |
17.5 |
107 |
17.5 |
15.9 |
14.6 |
13.4 |
12.2 |
|
12.7 |
13.9 |
15.1 |
16.4 |
17.8 |
108 |
17.8 |
16.3 |
14.9 |
13.7 |
12.4 |
|
12.9 |
14.1 |
15.3 |
16.7 |
18.2 |
109 |
18.2 |
16.6 |
15.2 |
13.9 |
12.7 |
|
13.2 |
14.4 |
15.6 |
17.0 |
18.5 |
110 |
18.6 |
17.0 |
15.5 |
14.2 |
12.9 |
|
13.4 |
14.6 |
15.9 |
17.3 |
18.9 |
111 |
19.0 |
17.3 |
15.8 |
14.5 |
13.2 |
|
13.6 |
14.9 |
16.2 |
17.6 |
19.2 |
112 |
19.4 |
17.7 |
16.2 |
14.8 |
13.5 |
|
13.8 |
15.2 |
16.5 |
18.0 |
19.6 |
113 |
19.8 |
18.0 |
16.5 |
15.1 |
13.7 |
|
14.1 |
15.4 |
16.8 |
18.3 |
20.0 |
114 |
20.2 |
18.4 |
16.8 |
15.4 |
14.0 |
|
14.3 |
15.7 |
17.1 |
18.6 |
20.4 |
115 |
20.7 |
18.8 |
17.2 |
15.7 |
14.3 |
|
14.6 |
16.0 |
17.4 |
19.0 |
20.8 |
116 |
21.1 |
19.2 |
17.5 |
16.0 |
14.5 |
|
14.8 |
16.2 |
17.7 |
19.3 |
21.2 |
117 |
21.5 |
19.6 |
17.8 |
16.3 |
14.8 |
|
15.0 |
16.5 |
18.0 |
19.7 |
21.6 |
118 |
22.0 |
19.9 |
18.2 |
16.6 |
15.1 |
|
15.3 |
16.8 |
18.3 |
20.0 |
22.0 |
119 |
22.4 |
20.3 |
18.5 |
16.9 |
15.4 |
|
15.5 |
17.1 |
18.6 |
20.4 |
22.4 |
120 |
22.8 |
20.7 |
18.9 |
17.3 |
15.6 |
Anthropometry may not accurately diagnose oedematous malnutrition due to the added weight of the oedema fluid. Anthropometric measurements that have been used include height-forage, weight-for-age, weight-for-height, head circumference, mid-upper arm circumference, and skinfold thickness.
Height-for-age 11:
It is used to assess linear growth. Deficit indicates long-term, cumulative nutritional inadequacies. ([i])Children whose height-for-age indices fall below 90% of the median value (< –2 SD) of the WHO reference value are classified as stunted with those below 85% (<- 3 SD) beingsevere. (Error! Bookmark not defined.)Because deficit in height results from a long-term process, stunting denotes chronic malnutrition. Length is measured for children less than of age 2 years whilst standing height is done for others, Length is usually greater than standing height by 0.5cm but this difference is accounted for in most reference charts.
Weight-for-age index 12:
Ithas traditionally been used in defining malnutrition with children whose measurements fall below 80% of the median value (< – 2 SD) being classified as malnourished [6] Because low weight-for-age may be due to low height for-age (stunting), low weight-for-height (wasting), or both (global malnutrition), weight-for-age is not currently a recommended measurement to define acute malnutrition(Error! Bookmark not defined.,i)
Weight- for- height:
It's the most objective way of assessing for recent nutritive crunches. Its use carries the advantage of taking no knowledge of age which is frequently delicate to gain in utmost developing countries. Children whose measures fall below 80 of the median value (< – 2 SD) of the WHO reference value are classified as wasted with those below 70(< – 3SD) being severe. Weight- for- height is the current recommended dimension for defining acute malnutrition 13.
Mid-upper arm circumference (MUAC) 14:
It has been used as indispensable indicator for assessing the nutritive status of children especially where the collection of height and weight measures may be delicate as, for illustration, in exigency situations like exile heads and dearths. In these situations, a low MUAC, grounded on a fixed cut- off point of 12.5 cm has been used as a deputy for low weight- for- height or wasting for children lower than five times of age.
Figure 2: Mid-upper arm circumference
Head circumference:
It's measured as the longest dimension around the head in the occipital-frontal plane, may be used to assess for the rapid-fire brain growth that occurs in the first 2 times of life. nutritive scarcities during this period may reflect in faltering head circumference. later, it reflects nutritive state inadequately.
Skinfold consistence:
It's measured with skinfold callipers, assesses the consistence of the skin and subcutaneous fat and may therefore indicate nutritive stores. Classical spots of measures are over the triceps, biceps, sub scapula, and tummy. ([ii]) Skinfold consistence is extensively used for assessing rotundity among grown-ups ([iii]) 15.
Conclusion
Anthropometry is one of the extensively used individual ways to rule out malnutrition. It gives accurate results which helps to assess the state of malnutrition. Using this fashion, we can give community- grounded operation and apply substantiated nutritive plans to ameliorate nutritive status of the children.
Acknowledgement
All thanks and praises to God almighty for his innumerous, abundant and noway - ending blessings in completing this work. It's a proud privileged honour for us to express our heartful thanks and appreciativeness to all the persons who backed us directly or laterally through out of this review work as magnitude. Most importantly authors are thankful to cases and health care professionals.
Conflict of Interest:
Non-financial
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